Pacific Southwest Airlines (PSA) Flight 182, registration N533PS, was a Boeing 727-214 commercial airliner that collided over San Diego, California with a private Cessna 172 on September 25, 1978. The death toll of 144 makes it the deadliest aircraft disaster in Californian history to date, and it was the first Pacific Southwest Airlines incident involving fatalities. It was also the deadliest plane crash in the history of the United States until American Airlines Flight 191 went down eight months later.
The Boeing crashed into North Park, a San Diego neighborhood, killing all 135 on board. The two men aboard the Cessna died, as did seven people on the ground, including two children. Nine others on the ground were injured and 22 homes were destroyed or damaged.